{"id":7115,"date":"2025-08-29T00:51:54","date_gmt":"2025-08-28T21:21:54","guid":{"rendered":"https:\/\/afachemi.com\/?p=7115"},"modified":"2025-12-07T00:59:14","modified_gmt":"2025-12-06T21:29:14","slug":"cancer-causes-and-prevention","status":"publish","type":"post","link":"https:\/\/afachemi.com\/en\/cancer-causes-and-prevention\/","title":{"rendered":"Cancer, causes and prevention"},"content":{"rendered":"<p style=\"text-align: left;\">According to the latest statistics provided by the country&#8217;s healthcare system, the most common cancers in Iran after skin cancer are breast cancer in women and stomach cancer in men, and in both sexes, bladder cancer, colon and rectum cancer, and esophageal cancer. Esophageal cancer is more common in the northeast and northern part of the country and in cities such as Ardabil, Talesh, and Gonbad.<\/p>\n<h3 style=\"text-align: left;\">What is carcinogenesis?<\/h3>\n<p style=\"text-align: left;\">Carcinogenesis is the process by which cancer is formed. In this process, the carcinogen causes and spreads changes in the genetics and epigenetics of the cell, which ultimately leads to the entry of a cell into an uncontrolled reproductive cycle and therefore a malignant mass is formed. Cell division is a physiological process that occurs in many cells and in a specific region, and in the normal state, the ratio of cell proliferation and cell death is maintained in a specific and pre-programmed proportion (called the apoptosis process), which leads to the stability of the volume and density and compaction of the relevant organ and tissue. In fact, during the formation of tumors, the causative agent disrupts this programmed ratio.<\/p>\n<p style=\"text-align: left;\">These tumors can be benign and malignant. Benign tumors are tumors that do not invade other organs and are often not considered life-threatening unless they put pressure on nearby vital organs or cause physiological problems. For example, they cause an excessive increase in a specific hormone in the body. (For example, growth hormone, which causes acromegaly.) But malignant tumors invade other nearby organs and invade distant sites and are life-threatening (metastasize).<\/p>\n<p style=\"text-align: left;\">Usually, more than one mutation is important for malignancy, which causes multiple changes in the cell&#8217;s genome, causing that cell to not do its job properly and to multiply uncontrollably.<\/p>\n<p style=\"text-align: left;\">One of the known carcinogens in nature are some viruses (such as human papillomavirus: HPV), which make the cell susceptible to becoming cancerous by making changes in the host cell&#8217;s genome.<\/p>\n<h3 style=\"text-align: left;\">What is a carcinogen?<\/h3>\n<p style=\"text-align: left;\">Any substance that initiates the process of carcinogenesis described above is called a carcinogen. Many natural carcinogens are known, such as aflatoxin B1, produced by Aspergillus, which is found in stored vegetables, snacks, nuts, and peanut butter.<\/p>\n<p style=\"text-align: left;\">Viruses such as hepatitis B, human papillomavirus, and roseosarcomavirus are known to cause some cancers, and bacteria such as Helicobacter pylori, as well as worms such as OPISTHORCHIS VIVERINI, CLONORCHIS SINESIS. Dioxins and dioxin-like compounds such as benzene, dust from industrial activities, which contain dozens of carcinogens such as benzopyrenes, aldehydes such as formaldehyde (REACTIVE ALDEHYDES), vinyl chloride, etc., have been known to cause cancer since the 1930s.<\/p>\n<p style=\"text-align: left;\">There is another group of substances called cocarcinogens, which are not carcinogens themselves, but they intensify the activity and effect of carcinogens.<\/p>\n<p style=\"text-align: left;\">Radiation: Radiation can play a role in carcinogenesis based on their power to ionize tissue, the amount of exposure to that particular radiation, and the penetration of that radiation.<\/p>\n<p style=\"text-align: left;\">Radiation that has low ionizing properties may cause irreversible damage to cellular DNA, which leads to disorders in cellular replication and transcription, and this is the introduction to the production of malignancy and at least it can cause premature aging of the cell. Materials and foods prepared with electromagnetic waves such as microwaves, X-RAYs, and gamma rays are not carcinogenic.<\/p>\n<p style=\"text-align: left;\">Cooking and Carcinogens: Research shows that 32% of deaths from cancer can be reduced by making changes in diet and cooking methods. Of course, it is very difficult and complicated to examine all the details of the nutritional content in this regard, but it can be said that most foods contain both carcinogenic and non-carcinogenic or, in other words, cancer-fighting substances.<\/p>\n<p style=\"text-align: left;\">For example, numerous studies show that grilling meat at high temperatures for a long time causes the production of carcinogens in the meat.<\/p>\n<p style=\"text-align: left;\">Although all types of cooking of meat produce some heterocyclic amines (unless we cook the meat and eat it raw), it is recommended to cook the meat at a temperature below 100 degrees Celsius to minimize the production of these substances.<\/p>\n<p style=\"text-align: left;\">Canned and prepared foods also contain substances called nitrosamines, which have a known link to colon cancer. Grilling, smoking, and grilling meat and fish increase the levels of carcinogens called polycyclic aromatic hydrocarbons.<\/p>\n<p style=\"text-align: left;\">Baking, broiling, and grilling foods, especially starchy foods, produce significant concentrations of acrylamides in these foods, which are likely carcinogens, until they are tested.<\/p>\n<p style=\"text-align: left;\">Dairy products appear to have a protective role against colon cancer, especially unpasteurized and fresh varieties of these products.<\/p>\n<p style=\"text-align: left;\">Heating sugar with protein or fat produces substances called GLYCOTOXIN, which have been shown to accelerate cell aging, diabetes, and obesity. Tobacco smoke contains a variety of carcinogens that bind to cellular DNA and cause genetic mutations. Today, more than 45 chemicals suspected of causing cancer are known to be in tobacco smoke.<\/p>\n<p style=\"text-align: left;\">On the other hand, smoking increases the risk of kidney cancer and cancers of the oral cavity (lips, tongue, pharynx, and mouth), esophagus, larynx, and so on. Certainly, in addition to avoiding exposure to many environmental and dietary factors, you can combat these factors by eating healthy foods and eating plenty of them:<\/p>\n<p style=\"text-align: left;\">Mushrooms: Mushrooms have long had a special place in traditional Chinese herbal medicine. Because they have antibacterial, antiviral, anti-inflammatory, and anti-carcinogenic properties, mushrooms today play an important role in improving human health and preventing diseases, and many scientific studies have confirmed that mushrooms play an important role in stimulating apoptosis and the death of cancer cells.<\/p>\n<p style=\"text-align: left;\">Green tea: Because they contain polyphenols that fight cancer cells, they prevent these cells from spreading and spreading. In particular, green tea contains a special compound that inhibits an enzyme called dihydrofolate rhododendase, which is often the target of anticancer drugs. Like mushrooms, which have different types with different properties, green tea also has different types, each of which has its own anti-carcinogenic properties.<br \/>\nTurmeric: Turmeric is one of the most powerful anti-carcinogens among all types of spices. The active ingredient in this spice, curcumin, seems to play a role not only in preventing the formation of cancer cells, but also in treating some cancers. According to recent studies, using turmeric at the rate of one teaspoon per day can keep cancer away. According to studies by a researcher from India, turmeric can inhibit the estrogen-like properties of some pesticide residues that are found on some fruits and vegetables, traditional milk, water and other foods.<br \/>\nBroccoli, cabbage and turnip family: These substances are rich in glucosinolates, a sulfur-containing substance that has strong anti-cancer properties. In particular, recent studies have shown that the turnip family contains biologically active compounds that help to eliminate and eliminate carcinogens in a convergent manner to prevent damage to cellular DNA, and research has also indicated a significant reduction in the risk of gastrointestinal and lung cancers in consumers of turnips and the turnip family.<br \/>\nFresh garlic: Garlic contains a compound called ALLICIN that targets cancer cells without damaging healthy cells, and therefore people who regularly use this food in their diet are largely resistant to cancer. Previous research has also shown that garlic contains another effective substance called (DIALLYL DISULFIDE) that inhibits cancer cells, and New Zealand researchers also found that this substance stimulates the production of an enzyme in the intestine that prevents the growth and spread of cancer cells in the digestive tract and intestine.<br \/>\nWe have talked a lot about vitamin D so far, but it must be emphasized that vitamin D plays a significant role in the treatment and prevention of cancers. Today, based on thousands of credible research projects, we know that daily consumption of vitamin D as a dietary supplement or regular daily exposure to sunlight, which leads to the production of vitamin D in the body, can be effective in the prevention and treatment of breast, colon, rectal, and other cancers.<\/p>\n<p style=\"text-align: left;\">According to studies, daily intake of 1,100 international units of vitamin D3 in combination with 1,450 milligrams (mg) of calcium reduces the risk of various types of cancer by about 77%.<\/p>\n<p style=\"text-align: left;\">Other foods that have relatively strong anti-carcinogenic effects include potatoes, ginger, probiotics, onions, thyme oil, cayenne pepper, vitamin C, hemp oil, coconut oil.<\/p>\n<h3 style=\"text-align: left;\">Screening:<\/h3>\n<p style=\"text-align: left;\">Screening or disease detection for cancer actually includes a set of national programs in which, based on the prevalence of some important cancers and the facilities available to prevent them, a program is developed to find healthy people susceptible to a type of malignancy or people with the disease in the pre-symptomatic and treatable stages.<\/p>\n<p style=\"text-align: left;\">For example, for breast cancer, the proposed program is that every woman over the age of twenty should regularly examine her own breasts. The individual should be trained in health centers and by the family doctor or health center staff, and the individual should be asked to inform the family doctor or the relevant health centers of all changes. Between the ages of 30 and 39, they should be examined by a doctor every 3 years. From the age of 40, in addition to personal examinations, an examination by a doctor should be performed once a year and a mammogram should be performed once a year.<\/p>\n<p style=\"text-align: left;\">For colon and rectal cancers, it is recommended to start screening based on a pre-established schedule from the age of 50.<\/p>\n<p style=\"text-align: left;\">For prostate cancer in men, for people with a high risk (first-degree relative with prostate cancer) from the age of 45, and for people with a normal risk (no family history) from the age of 50, it is recommended to measure blood.<\/p>\n<p style=\"text-align: left;\">For endometrial cancer (uterus) in postmenopausal women, it is recommended to see their doctor immediately if any bleeding or spotting occurs. For cervical cancer in women, it is recommended to perform an annual POP SMEAR test.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to the latest statistics provided by the country&#8217;s healthcare system, the most common cancers in Iran after skin cancer include breast cancer in women and stomach cancer in men, respectively, and in both sexes, respectively.<\/p>\n","protected":false},"author":9,"featured_media":7117,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[49],"tags":[],"class_list":["post-7115","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical-pharma-en"],"_links":{"self":[{"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/posts\/7115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/comments?post=7115"}],"version-history":[{"count":1,"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/posts\/7115\/revisions"}],"predecessor-version":[{"id":7116,"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/posts\/7115\/revisions\/7116"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/media\/7117"}],"wp:attachment":[{"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/media?parent=7115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/categories?post=7115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/afachemi.com\/en\/wp-json\/wp\/v2\/tags?post=7115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}