30 pieces
Oral
8mg, 16mg
8 and 16 mg lined tablets
This medicine has been prescribed for your current condition, so do not use it in similar cases or recommend its use to others.
Before using this medicine, consult your doctor in the following cases:
If you are allergic to this medicine or any other substance such as food, preservatives, dyes, etc.
If you are taking antihistamines, monoamine oxidases, drugs to treat depression and Parkinson’s,
If you have diseases such as stomach ulcers, asthma, various skin allergies and hypotension.
Use during pregnancy and lactation:
Betahistine should not be used during pregnancy and lactation unless advised by a specialist.
Warnings:
Betahistine is contraindicated in people with pheochromocytoma. Betahistine is a synthetic analogue of histamine and may cause the release of catecholamines from the tumor and cause a severe increase in blood pressure.
Betahistine can cause indigestion in people with digestive problems such as stomach ulcers; therefore, it should be used with caution.
Betahistine is not well tolerated in people with asthma, so patient monitoring is required if used.
In people with hives, skin rashes, and allergic runny nose, betahistine can worsen symptoms.
Betahistine should be prescribed with caution in people with low blood pressure.
Patients with rare hereditary problems such as galactose intolerance or glucose-galactose malabsorption should not use betahistine.
Dosage:
The dosage of the drug is determined by the attending physician for each patient. However, the usual dosage of the drug is as follows.
In adults:
Dizziness and tinnitus:
Take 8 to 16 mg three times a day.
Children:
Betahistine is not prescribed for children and people under 18 years of age.
How to take the medicine:
The medicine can be taken with food or on an empty stomach, but to reduce digestive side effects, it is better to take it with food.
It is better to take the medicine at specific times of the day.
If you take more than the prescribed amount, see a doctor. Symptoms of severe dizziness, drowsiness, and abdominal pain can be signs of drug poisoning.
If you forget a dose, take it as soon as you remember. If it is almost time for the next dose, skip that dose and do not double the dose.
Avoid stopping the medicine suddenly.
Side effects:
In addition to the desired therapeutic effects, every medicine may have some unwanted side effects. If any of the following side effects occur, inform your doctor.
Important side effects that require doctor’s notice if they occur:
Severe allergic reactions such as swelling of the face, tongue, lips, difficulty breathing, itching and skin rashes, and low blood pressure.
Less common side effects:
Nausea and vomiting, indigestion, headache, abdominal pain and bloating.
Storage conditions:
Store the medicine at a temperature below 30 degrees Celsius, away from light and moisture.
Avoid using expired medicine.
Keep the medicine out of reach of children.
Drug forms and packaging:
This medicine is produced and supplied in the form of scored tablets containing 8 and 16 mg of betahistine dihydrochloride under the brand name Afaserk and in boxes of 30 by Afa Shimi Pharmaceutical Company.
Tehran, KM 5, Fateh Highway, Beginning of Noord Street, No. 13 Tel. 64059-021
Ref: BNF 73
Betahistine is a medication that is mainly prescribed to reduce the symptoms of Meniere’s disease – including vertigo, tinnitus, and hearing loss. This medication helps to improve symptoms by increasing blood flow to the inner ear and reducing fluid pressure in the endolymph (fluid inside the ear). International studies have shown that the use of betahistine can improve the quality of life of patients with inner ear disorders.
Betahistine acts as a histamine analogue. By stimulating histamine receptors (specifically as an H3 antagonist), it increases the release of neurotransmitters and ultimately increases blood flow to the inner ear. This increased blood flow helps to reduce fluid pressure in the ear and improve Meniere’s symptoms.
Betahistine is rapidly absorbed after oral administration. In the fasting state, the drug is completely absorbed, but its maximum plasma concentration usually occurs 1 to 2 hours after oral administration.
The drug is mainly distributed in the blood plasma and a small amount of it is transported to the body tissues. Betahecitin does not bind to plasma proteins (less than 5%).
Betahecitin is mainly metabolized in the liver. Its main metabolism is to the active form of betahecitin, which is converted by the liver to inactive metabolites.
The drug is mainly excreted in the urine. The half-life of betahecitin is about 3 to 4 hours, but it can persist for longer in some patients.
Betahecitin does not cross the blood-brain barrier, indicating that its effects are mainly in the inner ear and balance system.
Some other medications may interact with betahistine:
Antihistamines (may reduce the effect of betahistine)
Medicines related to blood pressure regulation
Some other medications related to the treatment of dizziness
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