Indomethacin capsule

Indomethacin

25 mg capsule and 75 mg extended-release coated tablet

This medicine has been prescribed for your current condition. Therefore, do not use it in similar cases or recommend its use to others.

General instructions:

Before taking this medicine, consult your doctor in the following cases:

In case of allergy to this medicine or other medicines or any other substance such as food additives, preservatives, dyes, etc.

Patients with heart disease, high blood pressure, active acute ulcer or chronic inflammation of the upper or lower gastrointestinal tract

In case of history of liver disease, kidney disease, asthma, epilepsy, mental disorders

Use during pregnancy and lactation:

Indomethacin should not be used during pregnancy and lactation except under the advice of a specialist.

Warnings:

While taking the medicine, avoid driving vehicles and using dangerous machinery.
Indomethacin should not be prescribed to patients who have previously shown hypersensitivity reactions to NSAIDs (e.g., asthma, bronchospasm, rhinitis, angioedema, or urticaria).
Indomethacin is contraindicated for the treatment of pain after coronary artery bypass graft surgery.
The safety and efficacy of indomethacin in children and adolescents under 14 years of age have not been established.
Periodic ophthalmological examinations are recommended in patients receiving indomethacin long-term because of corneal deposits and retinal disorders.
Patients should inform their physician prior to surgery and dental procedures because of the increased risk of bleeding.
Indomethacin, like all NSAIDs, may exacerbate hypertension and congestive heart failure and may increase the risk of cardiac thromboembolism, myocardial infarction, and stroke.
The elderly are at increased risk of serious adverse effects. If NSAIDs are considered essential, they should be used at the lowest effective dose for the shortest duration possible. During treatment with NSAIDs, the patient should be regularly monitored for gastrointestinal bleeding.
Concomitant use of indomethacin with drugs such as oral corticosteroids, anticoagulants such as warfarin, selective serotonin reuptake inhibitors, or antiplatelet agents such as aspirin can increase the risk of ulceration or bleeding.
Indomethacin increases the risk of aseptic meningitis in patients with systemic lupus erythematosus and mixed connective tissue disorders.
The use of indomethacin is contraindicated in the third trimester of pregnancy.
Indomethacin interacts with ACE inhibitors, angiotensin II antagonists, beta-blockers, cyclosporine, digoxin, diuretics, lithium, probenecid, NSAIDs, and methotrexate, and concomitant use can cause changes in their plasma levels.

Dosage:

The dosage of the drug is determined by the attending physician for each patient. But the usual dosage of the drug is as follows:

Moderate to severe pain and inflammation, rheumatic pain and other musculoskeletal disorders:

Capsules: Adults 50 to 200 mg per day in divided doses

Extended-release tablets: Adults 75 mg 1 to 2 times a day

Acute gout:

Capsules: Adults 150 to 200 mg per day in divided doses

Extended-release tablets: Adults 75 mg 1 to 2 times a day

How to use the drug:

To reduce the risk of digestive disorders, indomethacin should always be taken with food or antacids, and in chronic conditions, start treatment with a low dose and increase if necessary.

Avoid alcohol while taking indomethacin. Alcohol and smoking irritate the stomach and aggravate complications.

If you take more than the prescribed dose, see a doctor. Severe headache, dizziness, nausea, vomiting, mental confusion, numbness or weakness, and epigastric pain can be signs of drug poisoning.

Side effects:

Every drug, along with its desired therapeutic effects, may also have some unwanted side effects. If any of the following side effects occur, stop taking the drug immediately and inform your doctor.

Sudden allergic reactions such as swelling of the face, tongue, shortness of breath, angioedema, anaphylactic reactions and symptoms such as severe pain or burning in the stomach or abdomen, bloody or tarry stools, blood in the mouth, unusual bleeding or bruising and vomiting blood

General side effects:

Agranulocytosis, alopecia, anxiety, decreased appetite, arrhythmia, asthma, blood disorder, bone marrow disorders, chest pain, confusion, congestive heart failure, constipation, depression, diarrhea and vomiting, dizziness, drowsiness, movement disorder, eye pain, fatigue, hot flashes, gastrointestinal disorders, gynecomastia, hemolytic anemia, bleeding, hallucinations, inflammatory bowel disease, headache, hearing impairment, liver disorders, hypotension, insomnia, leukopenia, hyperhidrosis, muscular weakness, nausea, edema, peripheral neuropathy, speech disorder, palpitations, photosensitivity, pancreatitis, respiratory disorders, hyperglycemia, hyperkalemia, Severe skin reactions, thrombocytopenia, tinnitus, urinary abnormalities, dizziness, visual impairment, renal failure

Specific side effects:

Dysfunction, restlessness, pulmonary edema, perforation of sigmoid lesion

Storage conditions:

Store the product at a temperature below 30 degrees Celsius, away from light and moisture.

Keep the medicine out of the reach of children.

Avoid using expired medicine.

After use, do not throw any medicine in the sewer or non-recyclable waste to protect the environment.

Dosage forms and packaging:

This medicine is produced and supplied in the form of capsules containing 25 mg of indomethacin in boxes of 100 and as sustained-release coated tablets containing 75 mg of indomethacin in boxes of 30 by Afachemi Pharmaceutical Company.